Index of /download/homology/best_hits
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A_nidulans_FGSC_A4_S_cerevisiae_best_hits.txt 23-Jul-2010 23:39 64K
To determine orthology assignments between A. nidulans and S. cerevisiae,
we used InParanoid (http://inparanoid.sbc.su.se/), described in detail at
http://www.aspgd.org//download/homology/orthologs/.
For A. nidulans proteins that did not have an ortholog that meets
the strict criteria used to define orthology with S. cerevisiae proteins,
we used BLASTp, using the same parameters as were used by
InParanoid (-F \"m S\" -M BLOSUM80) with an expectation value (E) of 1e-5
to identify their best hit in the S. cerevisiae protein complement.
These best hits data are available in the same format as the files containing
the ortholog data. The ortholog files are available at
http://www.aspgd.org/download/homology/orthologs/
The best hits data are updated quaterly to ensure that the predictions are based
on the most up-to-date information.